
Weight loss medications have become a popular solution for those struggling to shed excess kilos, but could they come with an unexpected side effect—mental health issues?
With the rise of prescription drugs like Ozempic, Wegovy, and older appetite suppressants, concerns about their psychological impact have surfaced.
While these medications promise effective results, experts claim that some users have reported experiencing anxiety, depression, and mood swings, raising questions about the connection between weight loss drugs and mental health.
According to a 2023 study published in the Journal of Psychiatric Research, some weight-loss medications may influence neurotransmitters in the brain, potentially leading to changes in mood and behavior. The publication states that many appetite suppressants work by altering levels of dopamine and serotonin—chemicals that regulate emotions.
Psychiatrist Dr Emily Carter explains, “Any medication that affects brain chemistry has the potential to impact mental health. While some people tolerate weight loss drugs well, others may experience heightened anxiety or depressive symptoms. ”
One of the biggest concerns has been linked to GLP-1 receptor agonists like Ozempic and Wegovy, which were originally designed for diabetes management but are now widely used for weight loss.
The above psychiatrist mentions that some users have reported experiencing emotional blunting, mood swings, or even depressive episodes.
A report from the American Journal of Clinical Nutrition suggests that drastic weight loss itself, regardless of medication use, can sometimes contribute to psychological distress due to hormonal changes and shifts in body image perception.
Stimulant-based weight loss drugs, such as phentermine, have also been flagged for their potential to cause anxiety and insomnia, according to the Food and Drug Administration. The publication also warns that these medications may trigger mood disorders in susceptible individuals, particularly those with a history of mental health conditions.
Nutritionist Sarah Lopez notes, “Some people don’t realise that rapid changes in weight and appetite can affect their emotions just as much as their physical health.”
That said, not everyone who takes weight loss medication will experience mental health side effects. Many individuals benefit from these drugs without significant issues, especially when used under medical supervision.
Experts emphasise that those considering weight loss medication should discuss their mental health history with a doctor and monitor their emotional well-being throughout treatment. “If you notice mood changes, don’t ignore them,” Dr Emily advises.
While weight loss medications can be a valuable tool, understanding their potential psychological effects is crucial to making an informed decision.
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